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After anesthetization with isoflurane (isoflurane dosage was carefully adjusted according to body weight and physiological indicators to maintain a uniform anesthesia depth, minimizing its impact on liver enzyme levels), BLI was induced using the aforementioned model

[DOI] [PMC free article] [PubMed] [Google Scholar] 248.Gao J., Xiong B.R., Zhan B., Li S., Huang N.N., Zhan G.F

A high-caloric diet coupled with a sedentary lifestyle are the major contributing factors in the development of the insulin resistance and pancreatic -cell dysfunction

Its like the concept of Ozempic is there, but the difference is that its studied, theres safety profiles, theres FDA regulations, and stuff like that