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This can proceed as the advantageous application of the principle of vascular cytoprotection [129,130,131,132,133,134,135,136,137,138,139,140,141,142,168]

Antioxidant and pro-oxidant effects of alpha-lipoic acid and glutathione in oxidative stress

Keep vials tightly sealed until reconstitution

Elesclomol is widely recognized to induce copper overdose and cell death (139), by acting as a copper ion carrier with a hydrophilic pore in its centre, to which Cu2+ ions can bind easily, facilitating copper entry into cells, thus increasing the intracellular copper concentration (140), and this, in-turn increases ROS levels, triggering oxidative stress (141) and ultimately cell death