![oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients](https://www.preprints.org/frontend/picture/ms_xml/manuscript/b110c2bb56ba2ea747ec10961b2b4880/preprints-144336-g003.png)
oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients
Description
Most available studies are preclinical or conducted on small human samples, which limits the ability to conclusively state their long-term efficacy and safety
![oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients](https://www.researchgate.net/publication/341916731/figure/fig1/AS:898867700695040@1591318168173/Clinical-photograph-of-melasma-patients-in-the-TXA-group-taken-at-the-first-visit.png)
Glutathione supports antioxidant defence and skin health over time
![oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c6/5808366/e2fe8d07b1db/dp0801a04g004.jpg)
The MPIB NGS Core Facility (RRID:SCR_025746), MPIB Mass Spectrometry Facility (RRID:SCR_025745) and MPIB Bioinformatics Core Facility (RRID: SCR_025742) were used for this project
![oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients](https://figures.semanticscholar.org/83ea9a78414f20b1af8b6de501f6baa92c1cacae/3-Table3-1.png)
Perets, O
![oral glutathione melasma randomized trial Efficacy of an Supplement on Dark Spot Pigmentation in Healthy Caucasian Subjects: a Double Blind, Placebo-Controlled Clinical Study[v1] Clinical photograph of melasma patients](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-025-26693-8/MediaObjects/41598_2025_26693_Fig2_HTML.png)
