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When IGF1 LR3 binds to IGF-1 receptors on target cells, it starts a cascade of intracellular signaling pathways, including the PI3K/Akt pathway and the MAPK/ERK pathway, which regulate protein synthesis, glucose body function, and cell survival mechanisms

Int J Chron Obstruct Pulmon Dis 18:129137 Toki S, Abney M, Zhang J, Rusznak M, Warren CM, Newcomb DC et al (2024) Endogenous Glucagon-Like Peptide-1 receptor and Glucose-Dependent insulinotropic polypeptide receptor signaling inhibits Aeroallergen-Induced innate airway inflammation

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