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Tumor-derived cytokines, notably interleukins and TGF-, remodel the epigenetic architecture of Treg through signal dependent control of FOXP3 expression and chromatin remodeling, This reprogramming locks in Treg differentiation and stability, constraining antitumor immunity and advancing disease progression
Masenga et al., 2023), diabetes mellitus (Wronka et al., 2022), cardiovascular disease (Jin and Kang, 2024), neurodegenerative disease (Olufunmilayo et al., 2023), renal dysfunction (Ho and Shirakawa, 2023) and many other pathologies
Additionally, some studies have developed delirium prevention artificial intelligence models (AID) based on reinforcement learning to optimize the dosage of dexmedetomidine
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