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doi: 10.1038/s41591-021-01520-5 59 BastakiSMAAmirNAdeghateEOjhaS

The dynamic regulation of miRNAs during early embryonic development and implantation is further highlighted by the observation of differential expression of 526 miRNAs between embryonic outgrowths and blastocyst-stage embryos, including let-7b, miR-23a, miR-27a, miR-291a, miR-425, and miR-429 [274]

Figure 3 Based on the consistency between the activities of the six enzymes and the removal of BaP from the culture, fitting models were further applied that confirmed a correlation between BaP degradation and the enzyme activity, resulting in significant linear positive relationships with high confidence levels (Table 3)

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