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The compound exists in a legal gray zone as a research chemical legal to possess, unlawful to sell as a therapeutic product

Improved laboratory methods or consistent biomarkers (e.g., always measuring holotranscobalamin in addition to total B 12 , or using standardized assays for 25(OH)D) would reduce measurement variability

Based on this scale, the drug intake, the sudden onset and the dermatological examination, the patient was diagnosed with vitamin B12-induced acneiform eruption

Bedekovic et al., 2003
