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doi: 10.3389/fphar.2025.1662341 Received 09 July 2025 Accepted 28 August 2025 Published 25 September 2025 Volume 16 - 2025 Edited by Johnson O

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We investigated how purinergic signalling and redox regulation intersect, controlling exosome formation in neutrophil-like cells (NLCs) differentiated from the HL-60 cell line

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Continual oxidative insult creates a decline in DNA repair machinery including base-excision repair (BER) and mismatch repair (MMR) and promotes mtDNA mutations (Leandro et al., 2015)

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