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67 Axial loading, on the other hand, occurs during activities that involve vertical forces, such as landing from a jump or when an athletes foot strikes the ground with substantial force

The blockade of this signaling pathway with specific inhibitors abolished the increase of BDNF production, possibly via modulation of ERK1/2- CREB pathway

doi: 10.1016/j.parkreldis.2007.06.009

However, GSH is continually being regenerated by GSSG reductase, a mainly cytosolic but also mitochondrial and nuclear enzyme, using NAPDH as a co-factor [10]
