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Skin changes and temperature dysregulation leading to loss of turgor, dryness and therefore itching and surface breaks are common in cirrhosis and the use of moisturizers to improve hydration and maintain barrier integrity is always the first step toward reducing pruritus (4)

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The review included questionnaires and case reports that described people developing manic episodes and other mood symptoms such as agitation, alertness, insomnia, and impulsivity after very high, short-term intake of energy drinks (for example, six to nine small cans per day over days to weeks)
