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13 Additionally, the activity of NNMT in white adipose tissue is positively correlated with adiposity and insulin resistance, while NNMT knockdown in vivo protects against the development of diet-induced obesity and insulin resistance

Both eventually reach similar endpoints

This distinguishes it from GLP-1 medications, which in some patients have been associated with significant lean mass reduction alongside fat loss
[Google Scholar] 21.Salek R
