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68 Although the concentration of free copper in cells is almost negligible, it still has a potentially detrimental effect on cell membranes, proteins, and nucleic acids

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In human embryonic stem cells, CHAC2 is highly enriched and is crucial for maintaining self-renewal capacity

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they show no significant telomere erosion

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Adult stem cells are mainly in a quiescence state and are constantly exposed to DNA-damaging agents

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