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[1] [24] Although there is some evidence from meta-analyses that L-carnitine supplementation improved cardiac function in people with heart failure, there is insufficient research to determine its overall efficacy in lowering the risk or treating cardiovascular diseases

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Besides, numerous studies have showed that inhibition of GPX4 could increase the sensitivity of chemotherapy, radiotherapy, immunotherapy and nanotherapy by inducing lipid peroxidation and ferroptosis [227,228,229]

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