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In the CNS, CCL11 has been implicated in age-associated cognitive decline, psychiatric disorders, multiple sclerosis (MS), and Alzheimers disease (AD) (reviewed in: 27 )

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Preclinical work points to a mechanism centered on 3-adrenergic receptor modulation, enhanced lipolysis, and reduced lipogenesis, largely independent of the insulin- and IGF-1-related pathways associated with full-length HGH

Similarly, combining AOD-9604 with growth hormone secretagogues or other peptides may create synergistic body composition effects by enhancing different aspects of metabolism