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Vitamin C acts as a natural antioxidant by readily donating electrons to safeguard crucial biomolecules (proteins, lipids, carbohydrates, and nucleic acids) against oxidative damage arising from cellular metabolism (85)

Results Amelioration of symptoms and reduction of epidermal thickness of IMQ induced psoriatic skin lesions in Prx II-knockout mice The regulatory role of Prx II was studied in psoriasis models that were generated in Prx II +/+ and Prx II / mice by the application of IMQ on their backs

Alpha Lipoic Acid (ALA) Known as a universal antioxidant that helps regenerate other antioxidants in the body

when reduced by TRX, Ref-1 increases DNA binding affinity of several TFs, including AP-1, NF-B, ATF/CREB, Myb, and p53 [78]