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NSAIDgut microbiota interactions
found that lycopene pre-administration could modulate the TLR4/TRIF/NF-B pathway by significantly downregulating the expressions of TLR-4, TRIF, phosphorylated p65 proteins, which in turn suppresses the production of inflammatory cytokines IFN-, TNF-, IL-6, and IL-1 in colonic tissue, thereby reducing inflammation response in the context of UC(48)
Mohamadnejad M, Alimoghaddam K, Bagheri M, Ashrafi M, Abdollahzadeh L, Akhlaghpoor S, et al
The ergothioneine molecular structure is given in Figure 1
