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It is approved in over 30 countries for hepatitis B and C treatment and as an immune adjuvant

Additional limitations include limited geographic area, limited racial diversity, and a disproportionate number of heath care providers as subjects in the trial

Mechanical cues such as a stiff surrounding extracellular matrix are also important for HSC activation

10.1016/j.humpath.2013.04.009 39 NabetaM.AbeY.KagawaL.HaraguchiR.KitoK.UedaN.et al (2009)
