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Vitamin b12 plays a vital role in maintaining flourishing skin, hair, nail, gut and brain

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Increased plasma FFAs reduce glucose uptake stimulated by insulin, but the decrease of lipid content improves insulin activities in skeletal muscles, adipocytes, and the livers [4, 5]

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Key Points The insulin-like growth factor 1 ( IGF1 ) gene is a major target of growth hormone IGF1 binds the IGF1 receptor (IGF1R) with high affinity and the insulin receptor with low affinity

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Defective CL leads to mitochondrial dysfunction, which is associated with disrupted NAD + metabolism 304,305

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