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Ascorbic acid acts by scavenging the superoxide radical anion, hydrogen peroxide, hydroxyl radical, singlet oxygen, and reactive nitrogen oxide [38]

The therapeutic benefits of the phytocannabinoids are clearly demonstrated by the medical use of CBD (Epidiolex ) to prevent certain rare forms of childhood epilepsy, delta-9-THC (Marinol and Syndros ) to manage nausea/vomiting associated with cancer chemotherapy and counteract anorexia associated with weight loss in AIDS patients, and CBD + delta-9-THC (Sativex ) to relieve spasticity in MS

Moreover, glutamate can be further metabolized to produce -ketoglutarate (-KG)

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