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Namely, we should consider egr-1 gene both positive and negative association

The regulator is the primary gatekeeper, and the Institutional Review Board sits alongside it
MAPK10, BACE1, GSK3B, MAPK8, CSNK2A1, NOS2, IL1B, PIK3CD, and MAPK3 were enriched in the AD pathway (hsa05010)
