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Description
The SDS-unfolded states of rhodopsin

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Mitochondrial Vulnerability: Mitochondria cannot synthesise glutathione and depend entirely on membrane transporters for supply

Various MQC pathways are dysregulated in PD, including mitochondrial regeneration (biogenesis 11 , protein import 12 ), mitochondrial dynamics (fission, fusion) 13,14 mitochondria-derived vesicles 15 and mitochondrial removal (mitophagy) 7,16