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Finally, detailed comparison of the structures reported here with previously published X-ray structures reveal a possible reaction coordinate for ligand-dependent conformational changes in the active site and the C-terminus

Kinase assay was stopped by heating at 100 C for 5 min in SDS protein sample buffer

2002;283:G1257G1263

Similarly, it is suggested that Spirulina may prevent neurodegenerative changes caused by some drugs used to treat cancer and rheumatoid arthritis and may play a role in alleviating cerebellar damage in this process
