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Description
Dysregulation of this pathway leads to excessive cholesterol accumulation and contributes to hypercholesterolemia, a common feature of insulin resistance and metabolic syndrome

We show that the GPX1 active site sequence is substantially similar to a known M pro cleavage site, and is identified as a potential cysteine protease site by the Procleave algorithm

Similarly, the TRPV4 channel has been detected in the flagellum and acrosome of human spermatozoa and is involved in sperm capacitation associated with motility hyperactivation

Mondola P et al
