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Description
In addition, in the mitochondria, it is a cofactor of methylmalonyl-CoA mutase, the enzyme that catalyses the reversible isomerization of methylmalonyl-CoA to succinyl-CoA, an essential intermediate in the citric acid cycle (TCA, Krebs cycle)
This isn't speculation
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The affected nerves consist of unmyelinated C and lightly myelinated A fibers that comprise the sensory and autonomic peripheral nervous systems
