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An overload of iron in mitochondria stimulates the production of reactive oxygen species (ROS) via Fenton reactions, resulting in oxidative damage to mitochondrial DNA, proteins, and lipids
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Numerous studies show that exposure to cigarette smoke depletes the Glutathione in your cells while generating reactive oxygen species (e.g., free radicals)
These differences are caused in part by tissue-specific differences in expression and function of different glucose transporter (GLUT) proteins [15]
