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Ipamorelin, a selective ghrelin receptor agonist with pentapeptide structure (Aib-His-D-2-Nal-D-Phe-Lys-NH2), reaches peak plasma concentration 1530 minutes post-subcutaneous administration and maintains receptor occupancy for 90120 minutes before enzymatic degradation via dipeptidyl peptidase-4 (DPP-4) and neutral endopeptidase pathways

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