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[PMC free article] [PubMed] [Google Scholar] 274.Ito J.T., Lourenco J.D., Righetti R.F., Tiberio I., Prado C.M., Lopes F

Representative flow cytometry plots showing ( a ) CD8 T cells, ( b ) IE1 + virus specific CD8 T cells and ( c ) IE1 + SLEC (CD127 lo ) and MPEC (CD127 hi ) subsets in spleens of BALB/c mice infected with MCMV or vCD44BP (day 7 PI)

These distinct signaling activities of costimulatory domains, at least in part, drive the T cells carrying CARs with the 4-1BB domain towards T CM , whereas the presence of CD28 domains yields T EFF [57]

Ahmad A, Alkharfy KM, Jan BL, Ahad A, Ansari MA, Al-Jenoobi FI, et al
