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The non-covalent self-assembly of hydrophobic polystyrene with chemotherapy drugs allows for a certain degree of prediction and control of the mass ratio of the loaded drug to the nanocarrier [103]

Further definition of the genotype-selective activity in ferroptosis in cancer and the mechanisms involved are important to guide ferroptosis-based therapeutic intervention 58,60

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For example, Cardax, a novel synthetic AST derivative, displays enhanced water solubility and bioavailability compared to free AST [119]