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Detection of abacavir-induced structural alterations in human leukocyte antigen-B*57:01 using phage display

Here, we found that the neuronal conditional-knockout (KO) of glutamyl-cysteine-ligase catalytic-subunit (GCLC), a rate-limiting enzyme for glutathione synthesis, induced brain atrophy accompanied by neuronal loss and neuroinflammation

After 7 days of ageing (and 48 h of the culture), NOx fumigation lowered levels of GRp compared to the control (Fig

Activated microglia and astrocytes release proinflammatory cytokines, chemokines, and reactive oxygen species, contributing to synaptic dysfunction and neuronal death (Thakur et al., 2023)