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After 12 weeks of treatment, both ferulic acid and zopolrestat effectively mitigated hyperinsulinemia and hypertension, successfully restoring normal endothelial relaxation responses ( Geranyl acetate, a terpenoid compound, exhibited notable diuretic and anti-hyperuricemic effects in male rats, particularly at a dosage of 100 mg/kg

Hypoxia-responsive nanoparticles for tumor-specific starvation therapy via a two-pronged approach

Roflumilast, a cyclic nucleotide phosphodiesterase 4 inhibitor, protects against cerebrovascular endothelial injury following cerebral ischemia/reperfusion by activating the Notch1/Hes1 pathway

Berkemeyer et al