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Temporal and spatial changes in the microbiome following pediatric severe traumatic brain injury

After 1 h of incubation of NPs in HeLa cells, weak red fluorescence alone was observed due to insufficient cell uptake

Tumor necrosis factor-alpha signaling in macrophages

Therefore it is conceivable that the induction of HO-1 is negligible in the doses used in human studies, which are at least one to two orders of magnitude less than those used animal studies (see Clinical Studies), reinforcing the observation that care must be taken when extrapolating animal studies to the human circumstance
