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These approaches will be essential for developing drugs that can be used in chronic treatment settings and for patients with pre-existing anti-drug antibodies

Regulatory authorities require comprehensive impurity characterization, and peptide mapping via LC-MS/MS has become the gold standard for this purpose, as outlined in regulatory requirements for GLP-1 peptide characterization

doi: 10.1530/EJE-10-0961 244 PrimeauVRaftopoulosCMaiterD

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