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This discrepancy may arise because TEM directly assesses the physical size of air-dried exosomes, while the zetasizer determines their hydrodynamic diameter, which includes the influence of the surrounding liquid layer causing the observed slight increase in particle size [35]

Nonetheless, it is still unclear if they contribute to the protective effects of exercise, necessitating further comprehensive investigation

JAMA 313(9):961962 Forthun I, Waage S, Pallesen S, Moen BE, Bjorvatn B (2022) A shift to something better