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Nature 649 , 477486 (2025)

These pathways collectively improve IR, synaptic plasticity, and exert anti-inflammatory, antioxidant, anti-ERS, and anti-neuronal apoptosis effects

Normothermic machine perfusion helps to restore kidney function by delivering oxygen and nutrients at body temperature, potentially reducing ischaemiareperfusion injury

For older adults, caution is advised due to the higher likelihood of underlying health conditions or medication use that might interact with the peptide
