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These molecular events collectively shift adipocytes from a lipid-storing to an energy-dissipating phenotype

Clinical evidence demonstrates that L-carnitine supplementation reduces fasting blood glucose ( markedly reduced fasting blood glucose and insulin resistance indices while enhancing insulin sensitivity in NAFLD mice ( Mechanistic insights into L-carnitine's effects on insulin resistance include: Inhibition of NF-B-mediated chronic inflammation: NF-B signaling promotes systemic inflammation and directly interferes with insulin signaling pathways, exacerbating IR ( Synergistic upregulation of energy metabolism and insulin signaling genes: Salic et al

P., Chen, S

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