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Description
Oral Administration of S-acetyl-glutathione: Impact on the Levels of Glutathione in Plasma and in Erythrocytes of Healthy Volunteers

Irisin activates SIRT1 to deacetylate HIF-1, reducing lactate metabolism and cell apoptosis To explore how irisin regulates HIF-1 through SIRT1, we used co-immunoprecipitation to isolate HIF-1 and measured its acetylation status

By removing interactions we can take the model apart piece by piece so that we can understand how and why glutathione metabolism works the way it does

10.1016/j.chembiol.2003.10.010
