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10.1164/rccm.201409-1610OC 44 FromentyB.FischC.BersonA.LetteronP.LarreyD.PessayreD

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(1) This 16 amino acid peptide reportedly retains the disulfide bond between cysteine residues at positions analogous to Cys182 and Cys189 in the intact hGH molecule, corresponding to positions 7 and 14 within the peptide

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As with the atypical antipsychotics, which have new data showing a diversity of mechanisms of action, including on inflammation,85 brain-derived neurotrophic factor86 and oxidative stress,87 efficacy may turn out to be a summative interaction of effects on various pathways

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