glutathione s-transferase protein sequence The role of S-transferases in human disease pathogenesis and their current inhibitors RCSB PDB - 5GSS: HUMAN
Description
Nerve changes from a prolonged B12 deficiency can affect coordination and balance, leaving some people feeling unsteady, dizzy, or more prone to stumbling

Monothiol deglutathionylation mechanisms include CPYC-dependent reactions involving only the active site Cys that is closer to the N-terminus, as well as deglutathionylation via a poplar GRX with a CSYS active site (Couturier et al., 2009)

Astrocytes contribute to neurodegeneration by releasing neurotoxic molecules and disrupting neuronal equilibrium [287290]

Klimiuk A, Maciejczyk M, Choromanska M, Fejfer K, Waszkiewicz N, Zalewska A
