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Intl Thymic Malignancy Interest Group, 2010
But progesterone is not only about uterine protection
The raison dtre of the LOX metabolism of the epidermal barrier lipids is to promote the covalent binding of ceramides and formation of the CLE, 180,603 and as the evidence stands, a major component of the Cer-EOS oxidized through the 12( R )-LOX pathway is covalently bond via Michael addition to Cys residues in the skin barrier protein
Kalluri R, Zeisberg M
