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Therefore, ROS represent a double-edged sword in cancer biology, making their regulation a critical factor in tumor progression and therapy [3,10,11,12,13,14]

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Based on the results from Warburg, recent research has uncovered the multifaceted biological functions of lactic acid, including its role as an energy source that can be transported into cells [3,4,5], its involvement in promoting tumor angiogenesis [6,7,8,9], its ability to inhibit immune cells within the tumor microenvironment [10,11,12], and its function as a signaling molecule mediating intracellular and intercellular communication

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