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Philadelphia, PA, March 13, 1993

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A retrospective study from the Children's Hospital of Philadelphia analyzed the outcomes of 81 repeat CAR T-cell infusions (CARTr) for three indications: (1) relapse prevention in at-risk patients (peripheral B-cell recovery [BCR] or emergence of CD19-positive hematogones), (2) CD19-positive MRD emergence or relapse, and (3) failure to go into remission after initial CAR T-cell infusion.[199] Of 63 patients who received CARTr for relapse prevention, 52% achieved CR (BCR, 15 of 40 [38%]

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