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However, pro-inflammatory stimuli disrupt mitochondrial TCA cycling, causing the accumulation of citrate, which is exported to the cytoplasm for acetyl-CoA conversion, driving de novo lipogenesis (DNL) and LD biogenesis (94,95)

Common signs of B12 deficiency include fatigue, weakness, pale skin, shortness of breath, numbness or tingling in the hands and feet, difficulty maintaining balance, and cognitive issues like memory problems