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In hippocampal tissues, mRNA expression studies at 1 h and 24 h showed that strongly elevated (Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos3, Nos1) and decreased (Nos2, Nfkb) gene expression (Mapk1 not activated) may be a means by which BPC 157 may act [52]

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Risson E, Nobre AR, Maguer-Satta V, and Aguirre-Ghiso JA (2020)

The exploration of macrocycles for drug discoveryan underexploited structural class

For example, concurrent use with corticosteroids may amplify the potential for fluid retention or electrolyte imbalance, particularly sodium and water retention
