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Many Se-independent peroxidase reactions performed by GSTs in insects have been reported
Accordingly, AQP4-IgG was demonstrated to induce IL-6 production and release by astrocytes through the NFkB pathway (92)

Balint B, Jepchumba VK, Guant JL, Guant-Rodriguez RM (2020) Mechanisms of homocysteine-induced damage to the endothelial, medial and adventitial layers of the arterial wall

Furthermore, the treatment efficacy is diminished due to the occurrence of platinum resistance
