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Dapsone and nitrofurantoin are likely to be unsafe in patients with moderate to severe enzyme deficiency

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A central message of this chapter is that the carcinogenic hazard derives primarily from specific processing conditions extreme temperatures, inappropriate fuels, prolonged smoke contact rather than from the cultural practice of smoking or grilling per se

While moderate ROS levels promote tumorigenesis via DNA mutagenesis, excessive ROS accumulation induces cancer cell death through oxidative stress