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Lancet 387 , 14151426 (2016)
[DOI] [PubMed] [Google Scholar] 43.Abou-Raya A, el-Hallous D, Fayed H

In this investigation, we initially identified oridonin as a direct covalent inhibitor of GSH, setting it apart from other drugs that disrupt ROS by targeting proteins both upstream and downstream of GSH

Autonomic Shift: Over time, the repeated heat stress encourages a shift toward parasympathetic dominance, supporting better stress resilience
