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Such permanent micro-abrasion of the skin by demodex might lead to hypersensitivity in rosacea [54]

As a tumour suppressor protein, p53 halts the cell cycle by inducing the expression of cell cycle arrest genes such as p21, 14-3-3, wild-type p53-induced phosphatase 1 (WIP1), and Growth Arrest and DNA Damage-inducible 45 (GADD45), while suppressing the expression of cell cycle progression genes such as cyclin B1 [50]

Standard urine tests detect ethyl glucuronide (EtG), a byproduct of alcohol
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