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AHK-Cu (L-Alanyl-L-Histidyl-L-Lysine Copper) is a synthetic copper tripeptide developed for hair follicle stimulation
Similar to metformin, artemisinin shows its antitumor potential by decreasing HIF-1, which suppresses glycolysis in TC [203]
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The mesenchymal phenotype has also been connected with SMAD3 activity in BRAFi persisters, and SMAD3 signaling led to the acquisition of drug resistance via activation of known drug-resistance genes, such as EGFR and AXL 41
