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We performed a redox western blot, which preserves protein oxidation, to determine the relative oxidation state of peroxiredoxin 1 (PRDX1), a direct substrate of TRX and a surrogate for the detection of TRX activity (38, 39)
Oxidative stress arises from the excessive production of ROS and free radicals, leading to lipid peroxidation and liver cell damage (Sumida et al., 2013)
10.1093/jnen/nlv001 J
It has been demonstrated that the chelation of Cu 2+ and Fe 3+ by DHLA in the brain reduces free radical damage and may exert a protective action in the pathobiology of Alzheimers disease [17]
