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Chapter 107: Surgical Anatomy of the Pancreas
[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Larsen N, Vogensen FK, van den Berg FW, Nielsen DS, Andreasen AS, Pedersen BK, Al-Soud WA, Srensen SJ, Hansen LH, Jakobsen M

They should be consumed slowly and doses should be spaced evenly throughout the day to maximize tolerance
[73] The vast majority of valproate metabolism occurs in the liver
